Liquid chromatography mass spectrometry (LC-MS, or alternatively HPLC-MS) is an analytical chemistry technique that combines the physical separation capabilities of liquid chromatography (or HPLC) with the mass analysis capabilities of mass spectrometry (MS). LC-MS is a powerful technique that has very high sensitivity, making it useful in many applications. Its application is oriented towards the separation, general detection and potential identification of chemicals of particular masses in the presence of other chemicals (i.e., in complex mixtures), e.g., natural products from natural-products extracts, and pure substances from mixtures of chemical intermediates. Preparative LC-MS systems can be used for rapid mass-directed purification of specific substances from such mixtures that are important in basic research, and pharmaceutical, agrochemical, food, and other industries. Like gas chromatography mass spectrometry, it allows analysis and detection even of tiny amounts of a substance.
We test all the pesticides required by the state of Oregon. We offer research and development tests to growers/producers working on new products; while not sufficient for market sales it allows us to estimate concentrations to a finer degree and does not mandate fail reporting to the state. The majority of our analytes are detected on the LCMS system; only a handful are still done on the GCMS.